more birth defects : boys fathers diabetes2 drug metformin 3 months

Bainbridge OH

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Men who took the type 2 diabetes drug metformin three months before conceiving their children seem to have an increased risk of having sons with birth defects, new research finds. The study, a retroactive analysis of Denmark’s federal registry of healthcare data that was published Tuesday (March 29) in Annals of Internal Medicine, found a significantly increased risk of genital birth defects among boys whose fathers had filled a prescription for metformin—commonly branded as Glucophage, Riomet, and Glumetza—about three months prior to conception, roughly the duration of time it takes for sperm to mature. A correlation between birth defects and paternal metformin prescriptions was not seen in girls, according to the study. https://www.the-scientist.com/news-opinion/metformin-prescriptions-linked-to-sons-birth-defects-69849?utm_campaign=TS_DAILY_NEWSLETTER_2022&utm_medium=email&_hsmi=208440680&_hsenc=p2ANqtz-87_xll1-UrO0tkrx-URNBK9GiwjpbPmGehK9QYt0VO4RxgZLbzcwLzVqJdlGz1m_aUJBWkhRsnmljLm1974e6cr1OrRw&utm_content=208440680&utm_source=hs_email