Research Study on Anorexia, Payment Up to $525

San Diego CA

Description

ABOUT THE STUDY This research uses fMRI to investigate how dopamine medications affect reward processing in the brain. Functional Magnetic Resonance Imaging (fMRI) techniques use powerful magnetic fields that allow a scanner and a computer to take very detailed pictures of the structure of the brain and brain activation. WHAT YOU'LL BE ASKED TO DO Participation in this study includes questionnaires about mood, eating and behavior, a diagnostic interview, EKG and blood labs and 3 brain imaging study visits. At each of the brain imaging study visits participants spend one hour in the scanner. During the scan, participants will complete 2 tasks – a learning task and a taste task. At the beginning of each day participants will be administered one of two dopamine medications or placebo. COMPENSATION Participants are compensated up to $525 for completing all of the study procedures. WE’RE RECRUITING Females who have a current diagnosis of restricting type anorexia nervosa and are currently underweight as well at as controls who are at healthy weight with no major medical history or history of an eating disorder. ELIGIBLE PARTICIPANTS Inclusion Criteria for Anorexia Nervosa 18-29 years old Right-handed Meets diagnostic criteria for anorexia nervosa, restricting sub-type Has a body mass index (kg/m2) less than 18.0 Inclusion Criteria for Healthy Controls 18-29 years old Right-handed Healthy body weight between 90-110% average body weight since puberty Regular monthly menstrual cycle (if applicable) No major medical illness or medications (birth control is allowed) Individuals who are currently pregnant or breastfeeding or have metal devices, implants or braces are not eligible to participate. You can go to our study page on UCSD Clinical Trials website for more details and to request a screening: