Celebrating 50 Years of the Medical School: A Bedside to Bench Story

79 Waterman Street,Providence RI 02912

03 May, 2023

Description

The Lemley Family Leadership Lecture SeriesFeaturing Arthur Horwich ’72, ’75 M.D., Sterling Professor of Genetics and Pediatrics, Yale School of Medicine Arthur Horwich came to Brown in Fall 1969 and joined the Master of Medical Sciences (MMS) program. As a second-year student, he became interested in Frank Rothman’s biochemistry course and joined Mike Czech and John Fain in the Fain Fat Cell Factory in J. Walter Wilson Lab to try to understand metabolic aspects of brown fat thermogenesis. Horwich’s MMS class was the first to pursue preclinical and clinical training through Brown’s new M.D. program, and he graduated with the first cohort in 1975. In this talk, Horwich will share the story of how his Brown education and subsequent pediatric training and fellowships equipped him to make a bedside to bench discovery: first the discovery of a genetic mutant that could not correctly fold proteins and then the identification and structural analysis of the double-ring protein “machine” responsible for the mutation. Horwich will reflect on his career in medicine, discuss the direction of medical education and talk about scientific/medical advances we can hope for. Talk followed by a Q&A moderated by Mukesh K. Jain, M.D., Dean of Medicine and Biological Sciences. Reception to follow. The Lemley Family Leadership Lecture Series invites exceptional leaders who are preeminent in their field to campus to engage and inspire the University community. Established in 2020 through a generous gift made by Wayne C. Lemley ’80 Ph.D., the series features highly accomplished scholars, thought leaders, policymakers and practitioners who will inform, challenge and educate — advancing Brown’s commitment to promoting a vibrant intellectual environment. For more information about the Lemley Family Leadership Lecture Series and Arthur Horwich's biography, please visit lemley-lecture.brown.edu. ___ Closed captioning will be available. For additional questions about the event or to request special accommodations, please email [email protected].